Power PlayerIn a specially-reinforced niche in the Riffe Building, an 800-megahertz NMR Spectrometer, the most powerful machine of its kind now available, has been providing new opportunities for leading-edge research since October, 1997. Only the third such powerful spectrometer installed in the United States, this unit is the star of a state-wide initiative to install spectrometers or computer-access links to them on 17 Ohio campuses. Although several Ohio campuses, including Ohio State, already have 600-megahertz spectrometers, researchers say this larger machine is needed to advance structural studies of proteins, DNA, and other macro molecules. It promises to make Ohio a leader in NMR technology, which uses strong magnetic fields to measure the nuclear properties of atoms in both living and non-living matter. According to Senior Research Associate Charles Cottrell, who manages the facility, the instrument currently is being used by four groups of researchers at Ohio State, biochemist Mark Foster among them, as well as researchers at Kent State and Ohio University. |
|
It's a (Natural) Gas1997 was a landmark year for microbiology researchers Charles Daniels and John Reeve, who finished sequencing the entire genome of M. thermoautotrophicum, a methane-producing microorganism widely studied as representative of the methanogens that inhabit biodegradation facilities. Reeve and Daniels and their collaborators at Genome Therapeutics Corp, or GTC; (Waltham, MA) identified, sequenced and assembled all 2,000 genes in the microbe's DNA. They found that about 20 percent of these genes are new to science, offering opportunities for biotechnology products. Methane, also known as natural gas or biogas, is generated in the final step of waste treatment. The biodegradation of industrial, urban and agricultural waste materials, generating methane provides a major source of renewable energy. Although methane recovery is a globally-used biotechnology, the methane-producing organisms themselves are still not well understood on the molecular level. Which explains why, in 1994, the Department of Energy funded a $1 million dollar per year collaboration between the Ohio State University and GTC to determine the entire sequence of the M. thermoautotrophicum genome. With a thorough understanding of these microorganisms, the design of more efficient waste treatment and methane-producing facilities should be possible, the researchers say. Both researchers emphasize the primary goal of the study was to accumulate the genetic information needed to enhance and to control methane production, to help promote energy production without contributing to global warming. Methane is constantly being recovered at 130 different US landfills, including the one in Franklin County, but enormous potential still exists at nearly 700 other sites around the country. |
|
Remembering...Entomology Professor Emeritus Robert P. Holdsworth died August 8, 1997. Holdsworth earned his B.S. from Massachusetts State College in 1937 and his Ph.D. from Harvard in 1941. In his Ph.D. dissertation, he deciphered the structural origin of wing venation. During WWII, Holdsworth served with the U.S. Navy in Malaria Control Units in the South Pacific. After the war and a career in industry, Holdsworth joined Ohio State as an Extension entomologist in 1958, his responsibilities later changing to teaching and research. Holdsworth taught courses in economic, horticultural and general entomology. He did research on fruit insects, hoping to develop better ways to control apple insects and mite pests. His field research program at Overlook Orchard in Fairfield County made him a recognized leader in the integrated control of apple pests. It was estimated at the time that his research would save Ohio apple growers $450,000 per year. He was presented with a special achievement award by the Ohio Fruit Growers Association in 1981. Holdsworth retired in 1981, but kept in touch with friends and colleagues; in a letter sent to Entomology Department Chair Dave Denlinger last June, Holdsworth described his days at OSU as being his very best. |